Focuses on the methods used to study drug effects and mechanisms in biological systems. It provides essential knowledge for drug research and development.
A brief overview of each apparatus in their respective experiments with 3D Animation Simulations
The study of common laboratory animals, such as rats, mice, and rabbits, involves understanding their care, handling, and biological characteristics.
Maintaining laboratory animals involves ensuring their well-being through proper housing, nutrition, and care
Blood withdrawal is a common laboratory technique used to collect blood samples from animals for analysis.
The study of drug administration routes in mice and rats includes oral, intraperitoneal, intravenous, and subcutaneous methods.
This experiment examines how different drugs affect the ciliary movement in the frog’s oesophagus.
To study the Miosis, Mydriasis and local Anesthetic effects of drugs on Rabbit’s Eye
The Elevated Plus Maze assesses anti-anxiety effects in mice by measuring their exploration of open versus enclosed arms.
Investigating morphine’s pain-relieving properties in mice involves using the acetic acid-induced writhing test to measure its analgesic effects.
Determination of acute eye irritation/corrosion of a test substance involves applying it to the eye and observing for signs of irritation or damage over a specified period.
The study examines how hepatic microsomal enzyme inducers affect phenobarbitone sleeping time in mice.
Evaluation of a test substance for acute skin irritation and corrosion potential.
Assessment of anti-inflammatory drug efficacy using the carrageenan-induced paw edema model.
Investigation of morphine’s analgesic effects in mice using the hot plate method
Evaluation of antianxiety and antidepressant drug effects on experimental animals using an actophotometer.
Investigation of drug effects on frog heart using the perfusion method
Examination of drug effects on an isolated frog heart
Assessment of pyrogenic substances using the rabbit method.
DEMO: How to make ringer solution?
The Rabbit Pyrogen Test is a method used to detect pyrogens in pharmaceutical products by injecting the test substance into rabbits and measuring their body temperature response
Mice are small, rats are larger; male rats are typically bulkier than females
Routes of drug administration in rats and mice include oral, intravenous, intraperitoneal, and subcutaneous methods.
Different ways to Hold a Rabbit
Different ways to Hold a Rat
Different ways to hold guinea pig
Equipment's used for isolated and perfusion heart experiment
How to make Ringer Solution
Ethical handling of lab animals involves humane treatment and minimizing suffering; unethical handling causes unnecessary pain or distress.
Studying the Types of Pre-Clinical Experiments involves evaluating various methods such as in vitro tests, in vivo animal studies, and ex vivo analyses to assess a drug's safety and efficacy before human trials.
Assessing Anti-Anxiety Effects through the Elevated Plus Maze in Mice
Investigate the analgesic properties of morphine in mice using the tail-flick method
Anticonvulsant effect of drugs by PTZ method in mice
Evaluation of Phenytoin’s Anticonvulsant Efficacy Against Maximal Electroshock-Induced Convulsions in Rats
Study of Diazepam’s muscle relaxant effects on mice using the Rota-Rod apparatus to measure muscle grip strength
good laboratory practices in a pharmacology lab